The current study shows that prolotherapy with hypertonic dextrose or prolozone (intraarticular ozone injection) can be effectively used in the nonoperative management of patients with KOA. Prolotherapy is an injection therapy for the management of chronic...
" Of note: Dr. Hughes’ primary rationale for use of injected ozone, alongside its benefits to mitigate pain, is its safe and very potent antimicrobial effects as part of sterile technique. Ozone therapy can induce the following biological responses Improves...
The therapeutic efficacy of ozone therapy may be partly due the controlled and moderate oxidative stress produced by the reactions of ozone with several biological components. The line between effectiveness and toxicity of ozone may be dependent on the strength of the...